2 6 0

chapter 14

Electron Transportand Oxidative Phosphorylation

F I G U R E 1 4 -1 4

Structure of ATP synthase. The F] complex situated above the membrane consists of three or/S dimers and single

y , S

,

e

subunits. The membrane segment Fo, also known as a stalk, consists of H+ channels. Protons are conducted via the

C-subunit channels. The rotation of C-subunits relative to a subunit of the stalk drives the rotation of the y-subunit.

[Reproduced with permission from Y. Zhou, T. M. Duncan and R. L. Crass: Subunit rotation in

E sch erich ia co li

FoFi-ATP synthase during oxidative phosphorylation.

Proc. N atl. A cad. Sci.

94,

10583 (1997). [©1997 by the National

Academy of Sciences.]

F I G U R E 1 4 -1 5

Nucleotide binding conformational changes of Fi ATP synthase complex. See text for details. [Reproduced with

permission from Y. Zhou, T. M. Duncan and R. L. Crass: Subunit rotation in

E sch erich ia co li

FoFj-ATP synthase during

oxidative phosphorylation.

Proc. N atl. A ca d . Sci.

94,

10583 (1997). ©1997 by the National Academy of Sciences.]